Faculty Of Medicine

Blog For Young Doctors And Medical Students.

What is your medical diagnosis "8" ?

A 56 year old male was brought into the Emergency Department, he was comatose with hypothermia, hypotonia, hyporeflexia, hypotension, conjunctival injection , slow respiration, acidotic breathing, In ED he was administered Thiamine 100mg IV and get better.




  • What is your diagnosis?
  • What is the role of Thiamine in this case ?  

Answer : 

  • Alcohol intoxication
  • Thiamine prevents the development of Wernicke-Korsakoff syndrome




Find hundreds of medical spot diagnosis pictures for free in this link : "What is your diagnosis"

215 comments:

«Oldest   ‹Older   1 – 200 of 215   Newer›   Newest»
dr.yasser said...

ethanol poisoning
role of thiamine is antidote of ethanol make detoxication of it

Anonymous said...

alcohol toxicity which caused lactic acidosis, thyamine is used to generate TPP for detoxification of alcohol

Anonymous said...

mmmmm

Anonymous said...

Wernicke's encephalopathy from alcohol intoxication..
thiamin is essential for carbohydrate metabolism and is defficient with chronic alcoholism..the presesntation is a form of reversible thiamin deficiency

Anonymous said...

I think the man suffers from Alcohol intoxication(ethanol poisoning)
Thiamine is administered to prevent wernicke-korsokoff syndrome.

faye1029 said...

I would say the patient had Wernicke's encephalopathy due to alcohol intoxication. It is reversible.
Thiamine is a cofactor for several important enzymes and may also be involved in conduction of the axon potential along the axon and in synaptic transmission.

mkk said...

Symptoms are suggestive of hypoglycemia and not of wernickes or isolated thiamine def.
alcoholic, acute on chronic thiamine def. lead to hypoglycemia and thus the symptoms.
treated with dextrose and thiamine.

nimer nader said...

i think it is type of chemical toxicity and what i know ethanol or tramadol .
thiamine is be given to adjust all hyporeflexes here like low fever but imcrese CNS transmission

Elvanee said...

alcohol intoxication

Elvanee said...

Chronic alcohol intake leads to a deficiency of thiamine which in turn results in serious brain disorder, including Wernicke-korsakoff syndrome.
As thiamine plays an imprtant role as a cofactor in metabolism of carbohydrate, i think it is helpful in this case to prevent further CNS damage.

Anonymous said...

I confirm: alcohol intoxication

Anonymous said...

alchol intoxication

zaphod beeblebrox said...

Alcohol intoxication mostly ethanol
could also be coolant poisoning

Satyendra said...

Wernicke's encephalopathy
Thiamine is a cofactor for several important enzymes , its required for generation of TPP that is depleted in Alcoholics .
Thiamine should be given before Dextrose

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